![]() ![]() Vicks Nyquil cold and flunighttime relief – acetaminophen, dextromethorphan hydrobromide, and doxylaminesuccinate capsule, liquid filled.Over-the-counter (OTC) medications can be helpful when you come down with a cough, cold, or fever.MUCINEX – guaifenesin tablet,extended release.You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. This will help make sure you don’t accidentally use too much of the drug. If you take NyQuil, make sure you don’t take it with other drugs that contain acetaminophen. Many over-the-counter drugs also contain acetaminophen. ![]() Taking more than four doses of NyQuil in 24 hours can cause severe liver damage. NyQuil contains acetaminophen, which can cause significant liver damage if you overuse it. If your symptoms aren’t relieved after a week, contact your doctor and stop using these drugs.
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